Mounjaro Results After 4 Months

By month four on Mounjaro (tirzepatide), many people have reached a point where their dose is stable and their routine is more established. Experiences at this stage can vary significantly depending on dosing, adherence, lifestyle changes, and individual response.

This guide outlines what clinical studies and real-world experience suggest about the first 16 weeks, including common patterns and reasons outcomes differ.

If you are exploring whether Mounjaro treatment is right for you, start with our main Mounjaro UK treatment page.

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Medicspot Staff Author

Medicspot Staff Author

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Last Updated: Nov 24, 2025

Next Review: Oct 30, 2026

What’s different in month 4 on Mounjaro?

At this point, most users have settled into their target dose—typically 7.5 mg or 10 mg weekly. Hunger signals are often better managed, and users begin to notice how habits, rather than novelty, drive results. The focus for many shifts from rapid change to sustainable, long-term improvement.

Real Mounjaro patients' 4 month results

We analyzed data from patients after their fourth month (16 weekly doses) of Mounjaro. Here’s what we found:

  • Dose = most commonly 7.5mg or 10mg
  • Sample size: 1029 patients
  • Average weight loss after 2 months (all patients) = 9.5kg (20.9lbs)

Weight loss continued for the majority, though a few experienced plateaus. These are often overcome through routine adjustments or dose evaluation.

Use our Weight Loss Calculator below to find out how much you could lose in month 4 (and beyond) on Mounjaro.

See how much you could lose

Based on the results of a clinical study with 806 participants.

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What affects progress in month 4

Progress continues between 12 and 16 weeks, and may be shaped by:

  • Dose stability: 10 mg tends to show the strongest appetite control
  • Mental fatigue: It’s normal to feel less excited—structure helps
  • Plateau phases: Reassess calories, activity, or hydration
  • Routine mastery: The more consistent your day-to-day, the better the results
  • Engagement: patients engaging with the Medicspot behaviour change course and weekly whatsapp check-ins with a Medicspot Health Coach generally see more effective weight loss.

Common side effects in month 4

Most users report reduced or minimal side effects by this stage. However, some still notice:

  • Early satiety (feeling full quickly)
  • Occasional bloating or constipation
  • Minor fatigue after injections

Maintaining hydration and a balanced diet can help. If discomfort persists, speak with your healthcare provider.

Tips for success in month 4

Want to make the most of your first 4 months on Mounjaro? Here are some actionable tips:

  • Keep your “why” in focus; motivation naturally dips
  • Mix up meals to avoid diet boredom
  • Stay consistent with movement (even low-impact counts)
  • Reflect on wins beyond the scale (energy, mood, control)
  • Consider goal tracking apps or group accountability

Mounjaro month 4 results - FAQ's

Final thoughts & next steps

Four months on Mounjaro represents commitment, and the results reflect that. Whether you’ve lost 15 or 40+ pounds, what matters most is the transformation in how you approach food, movement, and wellness. Keep going!

If you’re ready to find out more then click here to see if you are eligible for Mounjaro, or click here to find out more about the medication itself.

Disclaimer

This article is for general information only and should not be used for the diagnosis or treatment of medical conditions. Medic Spot Limited has used all reasonable care in compiling the information but makes no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. In the event of an emergency, please call 999 for immediate assistance.

There is no guarantee of a specific weight loss medication being prescribed. Clinicians will review your online questionnaire and will recommend the most appropriate weight loss treatments for you based on your answers. In some cases the clinicians may contact you for additional information. See our Terms of Service for more information.

The weight loss journey with Medicspot

Today

Take our simple online assessment to see if you're eligible, and if you qualify, your medication will arrive swiftly at your door. Over 84% of our members start seeing the number on the scale actually move down in their first month – many tell us it's the first time they've felt real hope in years.

The only regret I have is not doing it sooner.
Natasha Love
Lost 2st 4lb in 3 months

1-6 Months

You'll work with your personal health coach to rebuild your relationship with food from the ground up. As the weight comes off, you'll notice you have more energy for the things that matter, sleep better and feel more confident in your own skin. Our members lose an average of 2st 3lb by month 6.

I've been able to control all my eating, the food noise has been non-existent.
Amanda
15 weeks into the Medicspot programme

6-12 Months

You can lose up to 26% of your body weight while building habits that stick. Our toolkit gives you practical ways to navigate real-life situations – busy weeks, social events, and stressful periods – so you can maintain your progress without feeling like you're walking on eggshells around food.

Down to 68.3kg from 100.4kg! Complete lifestyle change, ran a 10k this week and signed up to the Manchester marathon for next year!
Medicspot Member
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Real people, real results

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