Mounjaro Results After 1 Month

People starting Mounjaro (tirzepatide) often want to know what the first month might look like. Results can vary widely, and early changes are only one part of a longer treatment journey.

This page summarises what clinical studies and real-world experience suggest about the first 4 weeks on Mounjaro, including typical patterns, reasons for variability, and questions to discuss with your clinician.

If you are exploring whether Mounjaro treatment is right for you, start with our main Mounjaro UK treatment page.

Clinical experts in weight management

Supervised and supported treatment

Ongoing medical and behavioural support

What is Mounjaro and how does it work?

Mounjaro is a once-weekly injectable medication that mimics two hormones (GLP-1 and GIP). These hormones help regulate blood sugar and reduce appetite. It was originally approved for managing type 2 diabetes, but Mounjaro is also now approved (and widely used) off-label for weight loss. It works by slowing down digestion, increasing feelings of fullness, and helping your body respond more effectively to insulin.

Real Mounjaro patients' 1 month results

We analyzed data from patients after their first month (4 weekly doses) of Mounjaro. Here’s what we found:

  • Dose = 2.5mg (this is the starting dose for all patients)
  • Sample size: 1029 patients
  • Average 1 month weight loss (all patients) = 3.4kg (7.5lbs)

Patients who combined Mounjaro with mindful eating and light physical activity tended to see higher results – as did those who engaged with the Medicspot behaviour change course and weekly whatsapp check-ins with a Medicspot Health Coach.

Use our Weight Loss Calculator below to find out how much you could lose in month 1 (and beyond) on Mounjaro.

See how much you could lose

Based on the results of a clinical study with 806 participants.

What is your height?
Switch to metric
What is your weight?
Switch to metric

Video Transcript

I’ve struggled with my weight most of my adult life and now I’ve finally found something that actually works. It’s really suppressed my appetite and in doing so has made me make some really healthy choices. It just comes so naturally to me now to go for the healthier option over the unhealthy option. Also I’m not really finishing as much on my plate anymore and I just feel so much healthier and more energetic and I just feel really positive about the future.

Video Transcript

I had a work photo taken and I couldn’t believe the results just how much weight I’d put on and the picture that I saw I thought “that’s not me” – it’s time to do something about it.  I am now in my third week of taking 2.5 milligrams and I’ve lost 12 pounds so far. In terms of symptoms I don’t seem to be getting any, I seem to be feeling okay. I’m eating small regular meals so I don’t know if that’s actually what seems to help.  There’s a lot of support on here if you need it which I think works and we’re in a great WhatsApp group that’s very supportive and results seem to help each other so yes it’s really good.

Video Transcript

Hi I am on week four of taking the medication. I feel pretty good I’m down about 14 pounds so that’s keeping me really motivated. Side effects have been pretty minimal and yeah so I started the journey because I have been struggling with weight loss for most of my life and I just thought this might give me a good start for the beginning of the year and I think where I’m losing weight consistently it’s keeping me really motivated and wanted me to make healthy choices. The team have been amazing the support from influence been so good the answer email straight away and yeah really happy with the progress so far.

What can impact your results in month 1

Results can vary based on several factors:

  • Diet: Those who adopt lower-calorie or protein-rich diets typically see faster progress.
  • Exercise: Even mild activity like walking supports weight loss.
  • Consistency: Missing doses or overeating can affect results.
  • Engagement: patients engaging with the Medicspot behaviour change course and weekly whatsapp check-ins with a Medicspot Health Coach generally see more effective weight loss.

Tips for success in your first month on Mounjaro

Want to make the most of your first month on Mounjaro? Here are actionable tips:

  • Stick to your dosing schedule
  • Keep a food and symptom journal
  • Prioritize hydration and fiber-rich foods
  • Set realistic goals and track your progress
  • Join a support community for encouragement

Mounjaro month 1 results - FAQ's

Final thoughts

Mounjaro can deliver meaningful changes in just 30 days, especially when paired with healthy habits. If you’re not seeing dramatic results right away, don’t get discouraged. Small, steady progress adds up, and many users find their results accelerate after the first month.

If you’re ready to find out more then click here to see if you are eligible for Mounjaro, or click here to find out more about the medication itself.

Disclaimer

This article is for general information only and should not be used for the diagnosis or treatment of medical conditions. Medic Spot Limited has used all reasonable care in compiling the information but makes no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. In the event of an emergency, please call 999 for immediate assistance.

There is no guarantee of a specific weight loss medication being prescribed. Clinicians will review your online questionnaire and will recommend the most appropriate weight loss treatments for you based on your answers. In some cases the clinicians may contact you for additional information. See our Terms of Service for more information.

The weight loss journey with Medicspot

Today

Take our simple online assessment to see if you're eligible, and if you qualify, your medication will arrive swiftly at your door. Over 84% of our members start seeing the number on the scale actually move down in their first month – many tell us it's the first time they've felt real hope in years.

The only regret I have is not doing it sooner.
Natasha Love
Lost 2st 4lb in 3 months

1-6 Months

You'll work with your personal health coach to rebuild your relationship with food from the ground up. As the weight comes off, you'll notice you have more energy for the things that matter, sleep better and feel more confident in your own skin. Our members lose an average of 2st 3lb by month 6.

I've been able to control all my eating, the food noise has been non-existent.
Amanda
15 weeks into the Medicspot programme

6-12 Months

You can lose up to 26% of your body weight while building habits that stick. Our toolkit gives you practical ways to navigate real-life situations – busy weeks, social events, and stressful periods – so you can maintain your progress without feeling like you're walking on eggshells around food.

Down to 68.3kg from 100.4kg! Complete lifestyle change, ran a 10k this week and signed up to the Manchester marathon for next year!
Medicspot Member
Shared in our community WhatsApp group

Real people, real results

See what our members have to say