Reflux and GLP-1s: How to Reduce Discomfort Through Food Choices

GLP-1s delay how quickly food leaves the stomach. This helps control appetite but can also increase pressure on the valve that separates the stomach from the oesophagus. When that pressure rises, acid can move upward, causing a burning sensation or sour taste.

Larger meals, fatty foods, and lying down soon after eating tend to make symptoms worse.

• Burning sensation in the chest or throat after meals
• Sour taste or regurgitation
• Mild cough or throat clearing
• Discomfort when bending or lying flat

Most people experience these symptoms only occasionally, and they often ease as your body adjusts to the medication.

• Lean proteins
Examples: Chicken, white fish, tofu
Why they help: Light and easy to digest

• Soft carbohydrates
Examples: Oats, rice, sweet potato
Why they help: Gentle and filling

• Cooked vegetables
Examples: Carrots, spinach, courgette
Why they help: Easy on the stomach

• Non acidic fruit
Examples: Melon, banana, pears
Why they help: Less likely to irritate

• Healthy fats
Examples: Olive oil, avocado (small amounts)
Why they help: Promote fullness with moderation

These foods are less likely to increase acid production or delay emptying further.

Eat Smaller, Slower Meals

Smaller meals create less stomach pressure. Chew thoroughly and stop when comfortably full.
See: Portion Sizes on GLP-1s: How to Adapt When You Feel Full Sooner.

Avoid Lying Down After Eating

Stay upright for two hours after meals. Try a short walk instead.

Limit Fluids During Meals

Large amounts of liquid can expand the stomach and push acid upward. Sip water between meals instead.
Read more: Hydration on GLP-1s: Why It Matters and How to Stay On Track.

Eat Mindfully

Slow down and take your time when eating, rest between bites, and listen to early signs of fullness.
See: Meal Timing on GLP-1s: Listening to Hunger Cues Safely.

Track Trigger Foods

Not everyone reacts to the same foods. Keeping a diary can help identify personal triggers.

If reflux combines with nausea, bloating, or constipation:

• Keep meals small and evenly spaced.
  
• Choose bland, low-fat foods like porridge, rice, or soups.
  
• Avoid late-night meals or heavy sauces.
• Adjust textures based on comfort.

See: Food Texture and GLP-1s: What Feels Comfortable and Why It Matters.

Speak to a clinician or your GP if:

• Reflux occurs more than twice per week
• You have difficulty swallowing or ongoing chest discomfort
• Weight loss is faster than expected or appetite drops sharply
• Over-the-counter remedies no longer help

Medicspot clinicians can review your symptoms, medication timing, and dietary habits to ensure your treatment remains safe and comfortable.

• Reflux can be common with GLP-1s but usually improves with dietary changes.
• Eat smaller, slower meals and avoid lying down soon after eating.
• Limit rich, acidic, and fizzy foods if they worsen symptoms.
• Stay hydrated between meals and note your personal triggers.
• Seek support if symptoms persist or affect your quality of life.

You don’t have to live with reflux while on GLP-1 medication. With small adjustments to food choice and meal timing, most people find relief quickly. Medicspot clinicians and health coaches can help you identify triggers, fine-tune your diet, and feel comfortable again while staying on track with your goals. Contact your GP or healthcare provider if these self-help steps do not improve your symptoms or if symptoms last longer than a few weeks.

If you’re not currently a Medicspot member but would like to join us then take our quick online weight loss assessment.