Mounjaro Maintenance Dose For UK Patients

A Mounjaro maintenance dose refers to the stable weekly dose you stay on after the active weight loss phase, once appetite patterns feel more predictable.

It’s different from the titration phase, where doses gradually increase. In the maintenance phase, the goal becomes preserving weight loss, managing appetite, and preventing weight regain. For some people, a Mounjaro maintenance dose is used for weight loss stability; for others, it’s mainly about maintaining metabolic improvement, such as better blood sugar control and insulin sensitivity¹.

People living with obesity know this truth better than anyone:

Losing weight is one challenge. Keeping it off is another.

Here’s why many choose a Mounjaro maintenance dose after weight loss:

After weight loss, the body often pushes back, increasing hunger, slowing metabolism, and making cravings louder.

Clinical trials with GLP-1-based medicines show that weight regain is common once treatment stops, especially without ongoing support².

A maintenance Mounjaro dose helps calm those signals so the weight you’ve lost is easier to maintain.

Tirzepatide improves insulin sensitivity and blood sugar control³. Many people want to keep these improvements steady after reaching a healthier weight.

The maintenance phase gives you time to build routines around food, movement and mindset, without the fear of sliding backwards as soon as the injections stop. NICE also emphasises that tirzepatide for obesity should be used alongside lifestyle support, not in isolation⁴.

After years of cycles, a maintenance dose can give a sense of confidence and stability while you adjust to living at a lower weight, particularly if you’ve previously regained weight after diets or other programmes⁵.

You may be ready to switch to a Mounjaro maintenance dose after goal weight when:

• You’ve achieved (or are very close to) your target
• Your hunger levels are calmer
• You’re stable on your current weekly dose
• You no longer need upward titration
• You and your clinician agree that the focus has moved from weight loss to weight maintenance
  

Some people transition to a maintenance dose when Mounjaro has helped them achieve a BMI of 25 or lower, typically within a BMI range of 21 to 24.9, although NICE-funded NHS use is restricted to higher BMI groups with weight-related comorbidities⁶.

Not all Mounjaro maintenance providers offer support once you achieve a healthy BMI. Many providers stop prescribing entirely.

We don’t take a one-size-fits-all view.

Our clinicians will continue prescribing if:

• It’s safe and clinically appropriate
• You meet prescribing criteria
• You can show evidence of previous Mounjaro prescriptions

We pair your Mounjaro maintenance dose with:

• Weekly WhatsApp check-ins from your dedicated health coach
• Support, tips, and encouragement from our member community
• “Life After GLP-1s” essential nutrition course
• Behaviour change and mindset coaching

To prescribe safely, we require:

Eligibility

• A BMI of at least 21
• Recent full body clothed photo
• Proof of your previous prescription (pen photo, start date, dispensing history)

When we may not be able to prescribe

• Your BMI is 20 or under
• You have a history of pancreatitis, kidney problems, liver or gall bladder problems, digestive paralysis or ventricular heart failure¹
• You’re pregnant or breastfeeding
• You have severe GI conditions
• You can’t provide evidence of safe prior use
• Continuing would be clinically unsafe

Our decisions always prioritise your long-term health.

Many people ask about the Mounjaro maintenance dose cost. Our prices start from £199 for the 2.5mg dose, and every order includes free next working day delivery when placed before 1pm Monday to Friday.

What makes our approach different is what you receive beyond the medication.

With our maintenance plans, you get medical care, weekly health coach check-ins, behaviour change support, and access to our member community throughout your maintenance phase. This reflects the “wraparound” model recommended when tirzepatide is used for obesity in the NHS⁴.

And when you eventually decide to come off Mounjaro completely, you won’t lose support – you’ll receive 12 months of free aftercare and coaching to help keep your weight stable, manage appetite changes, and maintain all the progress you’ve worked for.

It’s simple, complete the online assessment and upload the required evidence of your current prescription. This includes:

• A photo of your pen
• Your previous dose
• The date you started on Mounjaro
• The last dispense date

You can retrieve this from your old provider’s online portal. Once approved, you can continue on your existing dose or discuss transitioning to a maintenance or tapering plan.

Prices start from £199/month for the 2.5mg dose, including:

• Medication
• Weekly coaching and check-ins
• Free, discreet delivery
• Behaviour change resources
• Access to support groups
• And 12 months of free coaching if you taper off completely after reaching your goal weight

There are no hidden fees.

Some people may stay on a stable dose for an extended period if clinically appropriate. Others taper slowly over several months. Your clinician will help determine what is safest based on your:

• BMI
• Weight history
• Appetite
• Side effects
• Goals
• Medical background

There’s no pressure to stop before you’re ready, and there’s also no pressure to stay on medication longer than necessary.

If hunger suddenly becomes stronger, message your coach during your weekly check-in. We may recommend:

• A temporary dosage increase
• Additional coaching support
• Appetite management strategies
• Adjusting your tapering schedule
• Checking for medical factors like stress, sleep changes, or medications that influence appetite

You’re not expected to solve this alone.

Reaching your goal weight is an incredible milestone, but it’s not the end of your journey. Whether you stay on a maintenance dose, taper down gradually, or stop Mounjaro entirely, what matters most is having the right support as your body adjusts and your habits settle.

With Medicspot, you’re not left to figure this out alone.

You can continue with a personalised Mounjaro maintenance plan, or, if you choose to come off the medication completely after reaching your goal, you’ll receive 12 months of free coaching to help you stay steady, confident, and in control.

¹ EMC. Mounjaro 2.5mg KwikPen – Patient Information Leaflet. Updated 2025. Last accessed November 2025. [https://www.medicines.org.uk/emc/files/pil.15481.pdf]

² Wilding JPH, et al. Weight regain and cardiometabolic effects after withdrawal of semaglutide: the STEP 1 trial extension. Diabetes Obes Metab. 2022;24(8):1553–1564. Last accessed November 2025. [https://pubmed.ncbi.nlm.nih.gov/35441470/]

³ Diabetes UK. Mounjaro – uses, how it works and side effects. Last accessed November 2025. [https://www.diabetes.org.uk/about-diabetes/looking-after-diabetes/treatments/tablets-and-medication/glp-1/mounjaro]

⁴ NHS England. Interim commissioning guidance – Implementation of NICE TA1026 for tirzepatide (Mounjaro®) for obesity. March 2025. Last accessed November 2025. [https://www.england.nhs.uk/wp-content/uploads/2025/03/PRN01879-interim-commissioning-guidance-implementation-of-the-nice-technology-appraisal-ta1026-and-the-NICE-fu.pdf]

⁵ Wu H, et al. Trajectory of body weight after drug discontinuation in anti-obesity medication users: a systematic review and meta-analysis. BMC Medicine. Last accessed November 2025. [https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-025-04200-0]

⁶ National Institute for Health and Care Excellence (NICE). Tirzepatide for managing overweight and obesity (TA1026) – Recommendations. 23 December 2024; last reviewed 1 September 2025. Last accessed November 2025. [https://www.nice.org.uk/guidance/ta1026/chapter/1-Recommendations]

This article is for general information only and should not be used for the diagnosis or treatment of medical conditions. Medic Spot Limited has used all reasonable care in compiling the information but makes no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. In the event of an emergency, please call 999 for immediate assistance.

There is no guarantee of a specific weight loss medication being prescribed. Clinicians will review your online questionnaire and will recommend the most appropriate weight loss treatments for you based on your answers. In some cases the clinicians may contact you for additional information. See our Terms of Service for more information.