By month four on Mounjaro (tirzepatide), many users are experiencing the benefits of consistency: more stable weight loss, reduced food noise, and improved metabolic markers. This article shares verified weight loss averages, real-life patient stories, and expert guidance for managing progress at the 16-week mark.
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Medicspot Staff Author
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Medicspot Staff Author
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Last Updated:
Next Review: Jul 31, 2027
What’s different in month 4 on Mounjaro?
At this point, most users have settled into their target dose—typically 7.5 mg or 10 mg weekly. Hunger signals are often better managed, and users begin to notice how habits, rather than novelty, drive results. The focus for many shifts from rapid change to sustainable, long-term improvement.
Real Mounjaro patients' 4 month results
We analyzed data from patients after their fourth month (16 weekly doses) of Mounjaro. Here’s what we found:
- Dose = most commonly 7.5mg or 10mg
- Sample size: 1029 patients
- Average weight loss after 2 months (all patients) = 9.5kg (20.9lbs)
Weight loss continued for the majority, though a few experienced plateaus. These are often overcome through routine adjustments or dose evaluation.
Use our Weight Loss Calculator below to find out how much you could lose in month 4 (and beyond) on Mounjaro.
See how much you could lose
Based on the results of a peer-reviewed clinical study of 806 participants.
What affects progress in month 4
Progress continues between 12 and 16 weeks, and may be shaped by:
- Dose stability: 10 mg tends to show the strongest appetite control
- Mental fatigue: It’s normal to feel less excited—structure helps
- Plateau phases: Reassess calories, activity, or hydration
- Routine mastery: The more consistent your day-to-day, the better the results
- Engagement: patients engaging with the Medicspot behaviour change course and weekly whatsapp check-ins with a Medicspot Health Coach generally see more effective weight loss.
Common side effects in month 4
Most users report reduced or minimal side effects by this stage. However, some still notice:
- Early satiety (feeling full quickly)
- Occasional bloating or constipation
- Minor fatigue after injections
Maintaining hydration and a balanced diet can help. If discomfort persists, speak with your healthcare provider.
Tips for success in month 4
Want to make the most of your first 4 months on Mounjaro? Here are some actionable tips:
- Keep your “why” in focus; motivation naturally dips
- Mix up meals to avoid diet boredom
- Stay consistent with movement (even low-impact counts)
- Reflect on wins beyond the scale (energy, mood, control)
- Consider goal tracking apps or group accountability
Mounjaro month 4 results - FAQ's
Final thoughts & next steps
Four months on Mounjaro represents commitment, and the results reflect that. Whether you’ve lost 15 or 40+ pounds, what matters most is the transformation in how you approach food, movement, and wellness. Keep going!
If you’re ready to find out more then click here to see if you are eligible for Mounjaro, or click here to find out more about the medication itself.
Disclaimer
This article is for general information only and should not be used for the diagnosis or treatment of medical conditions. Medic Spot Limited has used all reasonable care in compiling the information but makes no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. In the event of an emergency, please call 999 for immediate assistance.
There is no guarantee of a specific weight loss medication being prescribed. Clinicians will review your online questionnaire alongside other independently validated medical information about you and will recommend the most appropriate weight loss treatments for you based on your answers. In some cases the clinicians may contact you for additional information. See Terms of Service for more information.
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