Mounjaro results 5 months

At 5 months on Mounjaro (tirzepatide), users often shift from early weight-loss milestones to long-term momentum. This phase is about refinement—maintaining habits, troubleshooting plateaus, and preparing for continued success. Here, we share updated patient data, video stories, and targeted strategies for making the most of month five.

Month 5: what changes?

By now, Mounjaro has become part of a routine. For many, weight loss begins to slow slightly but in a healthy, sustainable way. Cravings are generally reduced, and some users may experience renewed energy and mental clarity. It’s also a time when consistency can make or break continued success.

Real Mounjaro patients' 5 month results

We analyzed data from patients after their fifth month (20 weekly doses) of Mounjaro. Here’s what we found:

  • Dose = most commonly 7.5mg or 10mg
  • Sample size: 1029 patients
  • Average weight loss after 2 months (all patients) = 12.5kg (27.6lbs)

Weight loss continued for the majority, though a few experienced plateaus. These are often overcome through routine adjustments or dose evaluation.

Use our Weight Loss Calculator below to find out how much you could lose in month 5 (and beyond) on Mounjaro.

See how much you could lose

Based on the results of a peer-reviewed clinical study of 806 participants.

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What affects progress in month 5

Progress continues in month 5 (weeks 16 to 20), and may be shaped by:

  • Dose stability: 10 mg tends to show the strongest appetite control
  • Mental fatigue: It’s normal to feel less excited—structure helps
  • Plateau phases: Reassess calories, activity, or hydration
  • Routine mastery: The more consistent your day-to-day, the better the results
  • Engagement: patients engaging with the Medicspot behaviour change course and weekly whatsapp check-ins with a Medicspot Health Coach generally see more effective weight loss.

Common side effects in month 5

Side effects tend to diminish, but the following may persist or return with dose increases:

  • Mild nausea after injections
  • Slower digestion/fullness lasting longer
  • Occasional heartburn or constipation

Staying active, eating slowly, and continuing to hydrate are your best allies.

Tips for success in month 5

Want to make the most of your first 5 months on Mounjaro? Here are some actionable tips:

  • Start preparing for maintenance mode: what does sustainability look like for you?
  • Celebrate non-scale victories (NSVs): clothing fit, energy, strength
  • Add variety to meals and movement to prevent boredom
  • Lean into community or professional coaching if motivation dips
  • Revisit your goals monthly—what’s changed, and why?

Mounjaro month 5 results - FAQ's

Final thoughts & next steps

Five months on Mounjaro is an accomplishment. Whether you’re losing slowly or steadily, you’re building something sustainable. Stay consistent, listen to your body, and lean on your support system. This is more than weight loss, it’s a lifestyle transformation.

If you’re ready to find out more then click here to see if you are eligible for Mounjaro, or click here to find out more about the medication itself.

Disclaimer

This article is for general information only and should not be used for the diagnosis or treatment of medical conditions. Medic Spot Limited has used all reasonable care in compiling the information but makes no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. In the event of an emergency, please call 999 for immediate assistance.

There is no guarantee of a specific weight loss medication being prescribed. Clinicians will review your online questionnaire alongside other independently validated medical information about you and will recommend the most appropriate weight loss treatments for you based on your answers. In some cases the clinicians may contact you for additional information. See Terms of Service for more information.