Every person’s experience with Mounjaro is different. This page brings together real stories, month by month progress guides and patient videos so you can see how people describe their journey while using Mounjaro for weight loss. These insights can help you understand what to expect as treatment develops over time.
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Last Updated: Nov 24, 2025
Next Review: Jul 31, 2027
Do Weight Loss Treatments Work?
Yes, when used correctly under medical supervision, weight loss treatments can help many people lose a significant amount of weight. They are most effective when combined with lifestyle changes such as a healthy diet and regular physical activity.
Some treatments work by regulating appetite and insulin response (like Mounjaro or Wegovy), while others, like Orlistat, block fat absorption. Your results will depend on the treatment you choose, your starting weight, and how consistently you follow the plan.
Typical Weight Loss Treatment Results
GLP-1 Injections (e.g. Mounjaro, Wegovy): Up to 15-26% body weight loss over 12-18 months
Saxenda: Around 10% over 6-12 months
Orlistat (weight loss tablets): Around 5% over 6 months
These results vary by individual and should always be viewed alongside lifestyle changes.
Real Patient Success Stories
“I’ve struggled with my weight most of my adult life and now I’ve finally found something that actually works.
It’s really suppressed my appetite and in doing so has made me make some really healthy choices. It just comes so naturally to me now to go for the healthier option over the unhealthy option.
Also I’m not really finishing as much on my plate anymore and I just feel so much healthier and more energetic and I just feel really positive about the future.”
“”Bit of a NSV victory today. I weighed in and within 23 weeks I am within the healthy BMI bracket! I can’t believe it! I have gone from a BMI of 34.7 to 24.9!! My life has really changed”
Read more Medicspot Weight Loss Reviews here.
Comparing Pills vs Injections: Which Is More Effective?
Both weight loss pills and injections can help with weight loss, but they differ in how they work and who they’re best suited for.
Injections, such as Mounjaro or Wegovy, are generally more effective and are recommended for people with moderate to severe obesity. These are usually administered weekly or daily, depending on the medication.
On the other hand, tablets like Orlistat are typically used for people with mild to moderate weight loss goals. While they tend to be less effective than injections — with average weight loss around 5% — they can be a good option for those who prefer oral medication and are committed to using it with each meal.
How Long Before You See Results?
In terms of typical real world results:
Most patients see early weight loss within the first 4–8 weeks
Significant results typically appear within 12–16 weeks
Injections often work more quickly than tablets
Clinical studies have shown:
A 2022 trial on tirzepatide (Mounjaro) showed up to 22.5% weight loss in 72 weeks
Wegovy users lost on average 15% body weight in key studies
Orlistat resulted in 3-5% more weight loss vs lifestyle changes alone
Your doctor will review your progress and adjust the treatment if needed.
Next Steps: Check Eligibility or Book a Call
Ready to check if you are eligible? Take the Free Online Assessment now.
More questions? Want to speak with someone? Book a free call with our team today to discuss any questions you may have about Medicspot’s weight loss treatments.
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Explore Mounjaro progress at each stage
These guides share what patients commonly report at different points in their treatment. Experiences vary, but these pages provide practical insights and examples of what people notice over time.
1 month on Mounjaro
What people often notice during the first month, including early changes and common experiences.
2 months on Mounjaro
How treatment typically develops and what people tend to report in the second month.
3 months on Mounjaro
Insights from patients who reach the three month mark, including patterns and adjustments.
4 months on Mounjaro
Experiences shared by patients continuing treatment into the fourth month.
5 months on Mounjaro
What people describe around the five month point as treatment becomes more established.
6 months on Mounjaro
Longer term experiences and reflections from patients who have continued treatment for six months.
Weight Loss Treatment Results: Video Testimonials
"...something that actually works..."
"...time to do something about it..."
"...my food noise is at a zero..."
Real people, real results
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